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Point-of-care testing (POCT), or bedside testing is defined as medical diagnostic testing at or near the point of care—that is, at the time and place of patient care.[1] This contrasts with the historical pattern in which testing was wholly or mostly confined to the medical laboratory, which entailed sending off specimens away from the point of care and then waiting hours or days to learn the results, during which time care must continue without the desired information.
 
Point-of-care tests are simple medical tests that can be performed at the bedside. In many cases the simplicity was not achievable until technology developed not only to make a test possible at all but then also to mask its complexity. For example, various kinds of urine test strips have been available for decades, but portable ultrasonography did not reach the stage of being advanced, affordable, and widespread until the 2000s and 2010s. Today portable US is often viewed as a "simple" test, but there was nothing simple about it until the more complex technology was available. Similarly, pulse oximetry can test arterial oxygen saturation in a quick, simple, noninvasive, affordable way today, but in earlier eras this required an intraarterial needle puncture and a laboratory test; and rapid diagnostic tests such as malaria antigen detection tests rely on a state of the art in immunology that did not exist until recent decades. Thus, over decades, testing continues to move toward the point of care more than it formerly had been. A recent survey in five countries (Australia, Belgium, the Netherlands, the UK and the US) indicates that general practitioners / family doctors would like to use more POCTs.
 
The driving notion behind POCT is to bring the test conveniently and immediately to the patient. This increases the likelihood that the patient, physician, and care team will receive the results quicker, which allows for better immediate clinical management decisions to be made. POCT includes: blood glucose testing, blood gas and electrolytes analysis, rapid coagulation testing (PT/INR, Alere, Microvisk Ltd), rapid cardiac markers diagnostics (TRIAGE, Alere), drugs of abuse screening, urine strips testing, pregnancy testing, fecal occult blood analysis, food pathogens screening, hemoglobin diagnostics (HemoCue), infectious disease testing and cholesterol screening.
 
POCT is often accomplished through the use of transportable, portable, and handheld instruments (e.g., blood glucose meter, nerve conduction study device) and test kits (e.g., CRP, HBA1C, Homocystein, HIV salivary assay, etc.). Small bench analyzers or fixed equipment can also be used when a handheld device is not available—the goal is to collect the specimen and obtain the results in a very short period of time at or near the location of the patient so that the treatment plan can be adjusted as necessary before the patient leaves. Cheaper, faster, and smarter POCT devices have increased the use of POCT approaches by making it cost-effective for many diseases, such as diabetes, carpal tunnel syndrome (CTS) and acute coronary syndrome. Additionally, it is very desirable to measure various analytes simultaneously in the same specimen, allowing a rapid, low-cost, and reliable quantification. Therefore, multiplexed point-of-care testing (xPOCT) has become more important for medical diagnostics in the last decade.
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MSLRDT001 Dengue Combo Rapid Test Cassette
Product Name:  MSLRDT001 Dengue Combo Rapid Test Cassette
Latest Price:
Model No.:  MSLRDT001
Weight:  Net weight: Kg
Minimum Order Quantity:  1 Set Set/Sets
Supply Ability:  300 Sets per Year
Payment Terms:  T/T,L/C,D/A,D/P,Western Union,MoneyGram,PayPal
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Quick Details

The  Dengue  Combo  Test  Cassette  (Whole  Blood/Serum/Plasma)  is  a  rapid chromatographic immunoassay for the qualitative detection of NS1 antigen and IgG  and  IgM  antibodies  of  Dengue  virus  in  human  whole  blood,  serum,  or plasma as an aid in the diagnosis of Dengue infections. 

Packaging & Delivery

Packaging detail:Standard export package
Delivery detail:within 7-10 workdays after receipt of payment

Specifications

MSLRDT001 Dengue Combo Rapid Test Cassette

The  Dengue  Combo  Test  Cassette  (Whole  Blood/Serum/Plasma)  is  a  rapid chromatographic immunoassay for the qualitative detection of NS1 antigen and IgG  and  IgM  antibodies  of  Dengue  virus  in  human  whole  blood,  serum,  or plasma as an aid in the diagnosis of Dengue infections. 

Dengue  is  a  flavivirus,  transmitted  by  Aedes  aegypti  and  Aedes  albopictus 
mosquitoes. It is widely distributed throughout the tropical and subtropical areas 
of  the  world,1   and  causes  up  to   100  million  infections  annually.2   Classic Dengue infection is characterized by a sudden onset of fever, intense headache, myalgia, arthralgia and rash. 
Primary  Dengue  infection  causes  IgM  antibodies  to  increase  to  a  detectable level in 3 to 5 days after the onset of fever. IgM antibodies generally persist for 30  to  90  days.3  Most  Dengue  patients  in  endemic  regions  have  secondary infections,4  resulting   in  high   levels  of  specific   IgG  antibodies   prior  to   or simultaneous  with  IgM  response.5  Therefore,  the  detection  of  specific  anti-Dengue IgM and IgG antibodies can also help to distinguish between primary and secondary infections. NS1 is one of 7 Dengue Virus non-structural proteins which are thought to be involved in viral replication. NS1 exists as a monomer in its immature form but is rapidly processed in  the endoplasmic reticulum to form a stable dimer. A small 
amount  of  NS1  remains  associated  with  intracellular  organelles  where  it   is thought  to  be  involved  in  viral  replication.  The  rest  of  NS1  is  found either associated with the plasma membrane or secreted as a soluble hexadimer. NS1 is  essential  for  viral  viability  but  its  precise   biological  function  is  unknown. Antibodies raised in response to NS1 in viral infection can cross react    with cell surface antigens on epithelial cells and platelets and this has been implicated in the development of Dengue Hemorrhagic fever.
dengue rapid test

MSLRDT001 Dengue Combo Rapid Test Cassette

The Dengue IgG/IgM Rapid Test Cassette (Whole Blood/Serum/Plasma)   is a  qualitative   membrane-based  immunoassay   for  the   detection  of   Dengue antibodies  in   whole   blood,  serum,   or   plasma.  This   test  consists   of   two components, an IgG component and an IgM component. In the IgG component, anti-human IgG is coated in IgG test line region. During testing, the specimen reacts  with  Dengue  antigen-coated  particles in  the  test cassette.  The  mixture then migrates upward on the membrane chromatographically by capillary action and  reacts  with  the  anti-human  IgG  in  IgG  test  line  region.  If  the  specimen contains IgG antibodies to Dengue, a colored line     will appear in   IgG test line region. In the IgM component, anti-human IgM is coated in IgM test line region. During   testing,   the  specimen   reacts   with   anti-human   IgM.   Dengue   IgM antibodies, if present in the specimen, reacts with the anti-human IgM and the Dengue  antigen-coated  particles   in  the  test  cassette,   and  this  complex  is captured by the anti-human IgM, forming a colored line in IgM test line region.  Therefore, if the specimen contains Dengue IgG antibodies, a colored line will appear in IgG test line region. If the specimen contains Dengue IgM antibodies, a  colored  line  will  appear  in  IgM  test  line  region.  If  the  specimen  does  not contain Dengue antibodies, no colored line will appear in either of the test line regions, indicating a negative result. To serve as a procedural control, a colored line  will  always  appear  in  the  control  line  region,  indicating  that  the  proper volume of specimen has been added and membrane wicking has occurred.

MSLRDT001 Dengue Combo Rapid Test Cassette

The  Dengue  NS1  Rapid  Test  Cassette  (Whole  Blood/Serum/Plasma)  is a qualitative  membrane-based  immunoassay  for  the  detection  of  Dengue  NS1 antigen in whole blood, serum, or plasma. During testing, the specimen reacts with  Dengue   antibody-conjugate   in  the   test  cassette.   The  Gold   antibody conjugate will bind to Dengue antigen in the specimen sample which in turn will bind  with  Anti-Dengue  NS1  coated  on  the  membrane.  As  the  reagent  moves across the membrane, the Dengue NS1 antibody on the membrane will bind the antibody-antigen complex causing pale or dark pink line to form at the test line region of the test membrane. The intensity of the lines will vary depending upon the amount of antigen present in the sample. The appearance of pink line in the test region should be considered as positive result. 
【REAGENTS】
The   Dengue   IgG/IgM   Rapid   Test   Cassette   contains   Dengue   antigen conjugated gold colloid particles, anti-human IgM, anti-human IgG coated on the membrane.  
The  Dengue  NS1  Rapid  Test  Cassette contains anti-Dengue Ag conjugated colloid particles, anti-Dengue Ag coated on the membrane. 

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